BDBM361903 (R and S)-N-{1-[(4,4- difluoropiperidin-1- yl)carbonyl]propyl}-8-(1-ethyl- 5-methyl-1H-pyrazol-4-yl)-9- methyl-9H-purin-6-amine::US10221178, Compound 1-5

SMILES CCC(Nc1ncnc2n(C)c(nc12)-c1cnn(CC)c1C)C(=O)N1CCC(F)(F)CC1

InChI Key InChIKey=FTWVQWDCMSVRMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361903   

LigandPNGBDBM361903((R and S)-N-{1-[(4,4- difluoropiperidin-1- yl)carb...)
Affinity DataIC50: 9nMAssay Description:Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to column...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent