BDBM361888 US10221177, Compound 262

SMILES CC#CCn1c(=O)n(C)c2ncn([C@@H](C)C(=O)Nc3csc(n3)-c3ccc(nc3)N3CC4C(C3)C4(F)F)c2c1=O

InChI Key InChIKey=CVQHMRPOOCQEKI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361888   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Hydra Biosciences

US Patent

LigandBDBM361888(US10221177, Compound 262)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Compounds of Formula (I) inhibit the TRPA1 channel, as shown by measuring the in vitro inhibition of human TRPA1, provided in data tables shown in Ta...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/27/2019
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL