BDBM3617 4-N-(3-bromophenyl)pyrido[3,2-d]pyrimidine-4,6-diamine::6-amino-4-[(3-bromophenyl)amino]-pyrido[3,2-d]pyrimidine::CHEMBL300217::Pyrido[3,2-d]pyrimidine 11b

SMILES Nc1ccc2ncnc(Nc3cccc(Br)c3)c2n1

InChI Key InChIKey=PWLAEHXFQCNKSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3617   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3617(6-amino-4-[(3-bromophenyl)amino]-pyrido[3,2-d]pyri...)
Affinity DataIC50: 7.60nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3617(6-amino-4-[(3-bromophenyl)amino]-pyrido[3,2-d]pyri...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed