BDBM361517 N-(2-((3,5- difluoro-4- ((1R,3R)-6- fluoro-2-((1- fluorocyclopropyl) methyl)-3- methyl- 2,3,4,9- tetrahydro-1H- pyrido[3,4- b]indol-1- yl)pyridin-2- yl)oxy)ethyl)- 3- fluoropropan- 1-amine::US10221173, Example 109::US10590132, Example 109::US11046689, Example 109
SMILES C[C@@H]1Cc2c([nH]c3ccc(F)cc23)[C@H](N1CC1(F)CC1)c1c(F)cnc(OCCNCCCF)c1F
InChI Key InChIKey=BZOTUCBHQDTMIS-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 361517
Affinity DataIC50: 1.20nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:ERα: The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha-LBD (GST)) was assessed in competition assays us...More data for this Ligand-Target Pair