BDBM361408 (4-(6-((1H-pyrazolo [4,3-b]pyridin-3- yl)amino)benzo[d] isothiazol-3- yl)piperidin-1-yl) (tetrahydro- 2H-pyran-4- yl)methanone::US10221172, Example 72

SMILES O=C(C1CCOCC1)N1CCC(CC1)c1nsc2cc(Nc3n[nH]c4cccnc34)ccc12

InChI Key InChIKey=QUEDMLIGADKPNU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361408   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361408((4-(6-((1H-pyrazolo [4,3-b]pyridin-3- yl)amino)ben...)
Affinity DataEC50:  1.20E+3nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
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Date in BDB:
10/27/2019
Entry Details
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