BDBM361406 1-(4-(6-((1H- pyrazolo[3,4-b] pyridin-3-yl) amino)benzo[d]isothiazol- 3-yl)piperidin-1- yl)ethan-1-one::US10221172, Example 64

SMILES CC(=O)N1CCC(CC1)c1nsc2cc(Nc3n[nH]c4ncccc34)ccc12

InChI Key InChIKey=XKRLBRCVLIKLLE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361406   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361406(1-(4-(6-((1H- pyrazolo[3,4-b] pyridin-3-yl) amino)...)
Affinity DataEC50:  409nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
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Date in BDB:
10/27/2019
Entry Details
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