BDBM361395 3-(((3,3-difluorocyclobutyl) (methyl)amino)methyl)- N-(1H-pyrazolo[3,4-b] pyridin-3- yl)isothiazolo[4,5-b]pyridin- 6-amine::US10221172, Example 53

SMILES CN(Cc1nsc2cc(Nc3n[nH]c4ncccc34)cnc12)C1CC(F)(F)C1

InChI Key InChIKey=ATAGCXVTQSPQOO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361395   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361395(3-(((3,3-difluorocyclobutyl) (methyl)amino)methyl)...)
Affinity DataEC50:  568nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
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Date in BDB:
10/27/2019
Entry Details
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