BDBM361388 N-(1H-pyrazolo[3,4-b] pyrazin-3-yl)-3- (thiophen-3-yl)benzo[d] isothiazol-6-amine::US10221172, Example 46

SMILES N(c1n[nH]c2nccnc12)c1ccc2c(nsc2c1)-c1ccsc1

InChI Key InChIKey=NWIOCPGZWFLHDK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361388   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361388(N-(1H-pyrazolo[3,4-b] pyrazin-3-yl)-3- (thiophen-3...)
Affinity DataEC50:  144nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
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Date in BDB:
10/27/2019
Entry Details
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