BDBM361385 3-phenyl-N-(1H-pyrazolo [4,3-b]pyridin-3- yl)benzo[d]isothiazol-6- amine::US10221172, Example 43

SMILES N(c1n[nH]c2cccnc12)c1ccc2c(nsc2c1)-c1ccccc1

InChI Key InChIKey=RLYICIQYVUONDI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361385   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361385(3-phenyl-N-(1H-pyrazolo [4,3-b]pyridin-3- yl)benzo...)
Affinity DataEC50:  226nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent