BDBM361383 3-ethyl-N-(1H- pyrazolo[4,3-b] pyridin-3- yl)isothiazolo [4,5-b]pyridin-6- amine::US10221172, Example 41

SMILES CCc1nsc2cc(Nc3n[nH]c4cccnc34)cnc12

InChI Key InChIKey=ICJRXIDYPMXLFH-UHFFFAOYSA-N

Data  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361383   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361383(3-ethyl-N-(1H- pyrazolo[4,3-b] pyridin-3- yl)isoth...)
Affinity DataEC50:  38.3nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
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Date in BDB:
10/27/2019
Entry Details
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