BDBM361371 3-neopentyl-N-(1H- pyrazolo[3,4- b]pyridin-3-yl) isothiazolo[4,5-b] pyridin-6-amine::US10221172, Example 28

SMILES CC(C)(C)Cc1nsc2cc(Nc3n[nH]c4ncccc34)cnc12

InChI Key InChIKey=PXOCHTYCFWGKBE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361371   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361371(3-neopentyl-N-(1H- pyrazolo[3,4- b]pyridin-3-yl) i...)
Affinity DataEC50:  119nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
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Date in BDB:
10/27/2019
Entry Details
US Patent