BDBM361368 3-(tert-butyl)-N-(1H- pyrazolo[4,3-b]pyridin- 3-yl)benzo[d]isothiazol- 6-amine::US10221172, Example 25::US10221172, Example 26

SMILES CCCc1nsc2cc(Nc3n[nH]c4ncccc34)ccc12

InChI Key InChIKey=KEQMDXPFZDHGKM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 361368   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361368(US10221172, Example 26 | 3-(tert-butyl)-N-(1H- pyr...)
Affinity DataEC50:  220nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361368(US10221172, Example 26 | 3-(tert-butyl)-N-(1H- pyr...)
Affinity DataEC50:  329nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent