BDBM361352 (6-((1H-pyrazolo [4,3-b]pyridin-3- yl)amino)benzo[d] isothiazol-3-yl) (3,3-difluoropiperidin- 1-yl)methanone::US10221172, Example 9

SMILES FC1(F)CCCN(C1)C(=O)c1nsc2cc(Nc3n[nH]c4cccnc34)ccc12

InChI Key InChIKey=KYUNULHCIMTSMZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 361352   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM361352((6-((1H-pyrazolo [4,3-b]pyridin-3- yl)amino)benzo[...)
Affinity DataEC50:  233nMAssay Description:In the first mode, a range of concentrations of the disclosed compounds are added to cells, followed by a single fixed concentration of agonist. If t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
Go to US Patent