BDBM360845 Cyclobutyl (2-(2H-1,2,3-Triazol-2-yl)phenyl)((2R, 5R)-5-(5-cyclobutyloxazol-2-yl)-2-methylpiperidin- 1-yl)methanone::US9828368, Example 75

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)c1ncc(o1)C1CCC1

InChI Key InChIKey=RVFLBWKCKGGYJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 360845   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360845(US9828368, Example 75 | Cyclobutyl (2-(2H-1,2,3-Tr...)
Affinity DataIC50: 16nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details
Go to US Patent

TargetOrexin/Hypocretin receptor type 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360845(US9828368, Example 75 | Cyclobutyl (2-(2H-1,2,3-Tr...)
Affinity DataIC50: 59nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details
Go to US Patent