BDBM360823 5-((5-fluoropyrimidin-2- yl)ethynyl)-1-(2-oxo-2- ((1R,3S,5R)-3-(1-(2,2,2- trifluoroethyl)-1H-pyrazol- 3-ylcarbamoyl)-2- azabicyclo[3.1.0]hexan-2- yl)ethyl)-1H-indazole-3- carboxamide::US9828396, Compound 72

SMILES NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2ccn(CC(F)(F)F)n2)c2ccc(cc12)C#Cc1ncc(F)cn1

InChI Key InChIKey=LLOJSKXZJAGQFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360823   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM360823(US9828396, Compound 72 | 5-((5-fluoropyrimidin-2- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
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