BDBM360817 (S)-3-(2-(3-carbamoyl-5- (pyrimidin-2-ylethynyl)-1H- indazol-1-yl)acetyl)-N-(2'- chloro-2-fluorobiphenyl-3- yl)thiazolidine-2- carboxamide::US9828396, Compound 66

SMILES NC(=O)c1nn(CC(=O)N2CCS[C@H]2C(=O)Nc2cccc(c2F)-c2ccccc2Cl)c2ccc(cc12)C#Cc1ncccn1

InChI Key InChIKey=WWNGPGNIKVKNFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360817   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM360817(US9828396, Compound 66 | (S)-3-(2-(3-carbamoyl-5- ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
Go to US Patent