BDBM360354 US9828368, Example 16

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)c1nc(co1)C(C)(C)C

InChI Key InChIKey=IXWLXBTUDGKDJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 360354   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360354(US9828368, Example 16)
Affinity DataIC50: 60nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details
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TargetOrexin/Hypocretin receptor type 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360354(US9828368, Example 16)
Affinity DataIC50: 290nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details
Go to US Patent