BDBM360340 (2-(2H-1,2,3-Triazol-2-yl)phenyl)((2R,5R)-5-(4-(2- (hydroxymethyl)phenyl)oxazol-2-yl)-2- methylpiperidin-l-yl)methanone::US9828368, Example 5

SMILES CCc1ccccc1-c1coc(n1)[C@@H]1CC[C@@H](C)N(C1)C(=O)c1ccccc1-n1nccn1

InChI Key InChIKey=CQRVOQYQTMNUIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 360340   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360340(US9828368, Example 5 | (2-(2H-1,2,3-Triazol-2-yl)p...)
Affinity DataIC50: 30nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details
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TargetOrexin/Hypocretin receptor type 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM360340(US9828368, Example 5 | (2-(2H-1,2,3-Triazol-2-yl)p...)
Affinity DataIC50: 46nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2019
Entry Details
Go to US Patent