BDBM359978 (2R)-N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridinyl)-4H-1,2,4-triazol-3-yl)-::US10221162, Example 274.0::US10221162, Example 275.0

SMILES CO[C@@H](CS(=O)(=O)Nc1nnc(-c2cccc(OC)n2)n1-c1c(OC)cccc1OC)c1ccc(F)cc1S(C)(=O)=O

InChI Key InChIKey=BIXWDIJTOAIPDX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 359978   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM359978(US10221162, Example 274.0 | (2R)-N-(4-(2,6-dimetho...)
Affinity DataEC50:  0.120nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM359978(US10221162, Example 274.0 | (2R)-N-(4-(2,6-dimetho...)
Affinity DataEC50:  0.300nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent