BDBM359838 9-Bromo-3,4-dimethyl-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-2,5-dihydrobenzo[b]oxepine-7-carboxamide::US9822103, Example 86

SMILES CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(Br)c2OCC(C)=C(C)Cc2c1

InChI Key InChIKey=IXTSIHCXXNAUQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359838   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM359838(9-Bromo-3,4-dimethyl-N-((6-methyl-2-oxo-4-propyl-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:EZH2 Histone Methyl Transferase Assay: The effectiveness of compounds of the present invention as inhibitors of histone methyl transferases can be r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent