BDBM359832 9-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dimethyl-2,5-dihydrobenzo[b]oxepine-7-carboxamide::US9822103, Example 81

SMILES Cc1cc(C)c(CNC(=O)c2cc(Br)c3OCC(C)=C(C)Cc3c2)c(=O)[nH]1

InChI Key InChIKey=JKOXAERUTDGGMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359832   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM359832(9-Bromo-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:EZH2 Histone Methyl Transferase Assay: The effectiveness of compounds of the present invention as inhibitors of histone methyl transferases can be r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent