BDBM359746 US9822103, Example 17::t-Butyl 4-(5-(5-(((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)carbamoyl)-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)pyrimidin-2-yl)piperazine-1-carboxylate

SMILES Cc1cc(C)c(CNC(=O)c2cc3CC(C)(C)Oc3c(c2)-c2cnc(nc2)N2CCN(CC2)C(=O)OC(C)(C)C)c(=O)[nH]1

InChI Key InChIKey=OILBSIZMBBCZOF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 359746   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM359746(t-Butyl 4-(5-(5-(((4,6-dimethyl-2-oxo-1,2-dihydrop...)
Affinity DataIC50: 500nMAssay Description:EZH2 Histone Methyl Transferase Assay: The effectiveness of compounds of the present invention as inhibitors of histone methyl transferases can be r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
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