BDBM3597 (4Z)-4-[(3-bromophenyl)imino]-N,3-dimethyl-3H,4H-pyrido[4,3-d]pyrimidin-7-amine::N4-(3-bromophenyl)-3-methyl-7-(methylamino)-pyrido[4,3-d]pyrimidin-4(3H)-imine::Pyrido[4,3-d]pyrimidine 12

SMILES CNc1cc2ncn(C)\c(=N/c3cccc(Br)c3)c2cn1

InChI Key InChIKey=KGPJHDOZKFVFLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3597   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3597((4Z)-4-[(3-bromophenyl)imino]-N,3-dimethyl-3H,4H-p...)
Affinity DataIC50: 3.10nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2005
Entry Details Article
PubMed