BDBM35920 9,10-dihydroanthracene(DHA), 1a::9-(Aminomethyl)-9,10-dihydroanthracene::9-aminomethyl-9,10-dihydroanthracene::C-(9,10-Dihydro-anthracen-9-yl)-methylamine::CHEMBL47482

SMILES NCC1c2ccccc2Cc2ccccc12

InChI Key InChIKey=GEICAQNIOJFRQN-UHFFFAOYSA-N

Data  17 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 35920   

Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  20nMAssay Description:Binding affinity was performed using [3H]ketanserin as the radioligand and stably transfected NIH3T3 cells expressing the 5-hydroxytryptamine 2A rece...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor sites by using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  20nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor expressed NIH3T3 cells using [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2A receptor expressed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  20nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  43nMAssay Description:Binding affinity to 5-hydroxytryptamine 2C receptor using [3H]Mesulergine as radioligand in stably transfected NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Virginia Commonwealth University

LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi:  197nM ΔG°:  -9.14kcal/moleT: 2°CAssay Description:Aliquots of radioligand are dispensed into the wells of 96-well plates. Then, duplicate aliquots of the test and reference compound dilutions are add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to Norepinephrine transporter using [3H]-nisoxatine as radioligand in stably transfected NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to Serotonin transporter using [3H]-paroxetine as radioligand in stably transfected NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Mouse)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to Dopamine receptor D2 using [3H]spiperone as radioligand in stably transfected NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]paroxitine from SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM35920(CHEMBL47482 | 9-(Aminomethyl)-9,10-dihydroanthrace...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxitine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed