BDBM3592 7-Acetamido-4-[(3-bromophenyl)amino]pyrido[4,3-d]-pyrimidine::CHEMBL52418::N-{4-[(3-bromophenyl)amino]pyrido[4,3-d]pyrimidin-7-yl}acetamide::Pyrido[4,3-d]pyrimidine 5c

SMILES CC(=O)Nc1cc2ncnc(Nc3cccc(Br)c3)c2cn1

InChI Key InChIKey=KKLFLZHHIPZMHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3592   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3592(7-Acetamido-4-[(3-bromophenyl)amino]pyrido[4,3-d]-...)
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2005
Entry Details Article
PubMed