BDBM35852 acrylic acid derivative, 10

SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCCCOc1ccccc1

InChI Key InChIKey=RVLUXUBUNBILRZ-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 35852   

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Ono Pharmaceutical

LigandPNGBDBM35852(acrylic acid derivative, 10)
Affinity DataKi:  220nM EC50:  3.50E+3nMAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Ono Pharmaceutical

LigandPNGBDBM35852(acrylic acid derivative, 10)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.0 T: 2°CAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Ono Pharmaceutical

LigandPNGBDBM35852(acrylic acid derivative, 10)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.0 T: 2°CAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Ono Pharmaceutical

LigandPNGBDBM35852(acrylic acid derivative, 10)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed