BDBM3582 5-[(3-Bromophenyl)amino]-1H-pyrazolo[4,3-g]quinazoline::Anilinopyrimidine deriv. 7c::N-(3-bromophenyl)-1H-pyrazolo[4,3-g]quinazolin-5-amine::Pyrazoloquinazoline deriv. 20::Pyrazoloquinazoline deriv. 2a

SMILES Brc1cccc(Nc2ncnc3cc4[nH]ncc4cc23)c1

InChI Key InChIKey=ORCWMSOZENFEDR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3582   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3582(N-(3-bromophenyl)-1H-pyrazolo[4,3-g]quinazolin-5-a...)
Affinity DataIC50: 0.440nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3582(N-(3-bromophenyl)-1H-pyrazolo[4,3-g]quinazolin-5-a...)
Affinity DataIC50: 0.440nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3582(N-(3-bromophenyl)-1H-pyrazolo[4,3-g]quinazolin-5-a...)
Affinity DataIC50: 0.440nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3582(N-(3-bromophenyl)-1H-pyrazolo[4,3-g]quinazolin-5-a...)
Affinity DataIC50: 19.9nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed