BDBM358187 N-(3-(((6-methoxy-2-(2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl)benzofuran-4-yl)oxy)methyl)phenyl)-3-(trifluoromethoxy)benzamide::US10214544, Example 6

SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(NC(=O)c4cccc(OC(F)(F)F)c4)c3)cc(OC)cc2o1

InChI Key InChIKey=XHWVWTNCNSJIIM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 358187   

TargetProteinase-activated receptor 4(Human)
Universite De Montreal

US Patent
LigandPNGBDBM358187(US10214544, Example 6 | N-(3-(((6-methoxy-2-(2-met...)
Affinity DataEC50:  1.40nMAssay Description:FLIPR-based calcium mobilization assay in HEK293 cells was used to measure PAR4 antagonism, agonism, and selectivity against PAR1. The activity of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent