BDBM357720 N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimethyl-6-oxo-5,6,7,8-tetrahydro-2,7-naphthyridin-3-yl)methyl)acrylamide::US10214528, Example 24::US10738048, Example 24::US11014923, Example 24::US11667635, Example 24::US9890156, Example 24

SMILES COc1cc(OC)c(F)c(N2Cc3cnc(CNC(=O)C=C)cc3C(C)(C)C2=O)c1F

InChI Key InChIKey=NRKXDEYPXNONFT-UHFFFAOYSA-N

Data  20 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 357720   

TargetFibroblast growth factor receptor 3(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

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Date in BDB:
4/4/2021
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TargetFibroblast growth factor receptor 4(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

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Date in BDB:
7/9/2023
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TargetFibroblast growth factor receptor 3(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
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Date in BDB:
7/9/2023
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TargetFibroblast growth factor receptor 2(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
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In Depth
Date in BDB:
7/9/2023
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TargetFibroblast growth factor receptor 1(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
7/9/2023
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TargetFibroblast growth factor receptor 4(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
11/22/2021
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TargetFibroblast growth factor receptor 3(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/22/2021
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TargetFibroblast growth factor receptor 2(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/22/2021
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TargetFibroblast growth factor receptor 1(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/22/2021
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TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 115nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/4/2021
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TargetFibroblast growth factor receptor 1(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:TBDMore data for this Ligand-Target Pair

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UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
10/20/2019
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TargetFibroblast growth factor receptor 2(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
4/4/2021
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
4/4/2021
Entry Details
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TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 125nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
2/16/2020
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/16/2020
Entry Details
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TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/16/2020
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
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US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/16/2020
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TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 115nMAssay Description:TBDMore data for this Ligand-Target Pair

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UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

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Date in BDB:
10/20/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:TBDMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/20/2019
Entry Details
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TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent

LigandBDBM357720(N-((7-(2,6-difluoro-3,5-dimethoxyphenyl)-5,5-dimet...)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:TBDMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/20/2019
Entry Details
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