BDBM357498 US10214519, Example 242

SMILES Fc1ccc(Cl)c2nccc(-n3c(nc4c(cc(cc34)N3CCOCC3)-c3ncco3)C3CC3)c12

InChI Key InChIKey=VUDBNTIPAHZVRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 357498   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandPNGBDBM357498(US10214519, Example 242)
Affinity DataIC50: 6nMAssay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent