BDBM357247 Methyl 5-(5-amino-4-(1H-indole-2-carbonyl)-1H-pyrazol-1-yl)-1H-benzo[d]imidazole-2-carboxylate::US10214515, Example 7

SMILES COC(=O)c1nc2cc(ccc2[nH]1)-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N

InChI Key InChIKey=PGRWVLHMKFTXIP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 357247   

TargetFibroblast growth factor receptor 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357247(US10214515, Example 7 | Methyl 5-(5-amino-4-(1H-in...)
Affinity DataIC50: 30nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357247(US10214515, Example 7 | Methyl 5-(5-amino-4-(1H-in...)
Affinity DataIC50: 75.3nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357247(US10214515, Example 7 | Methyl 5-(5-amino-4-(1H-in...)
Affinity DataIC50: 100nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM357247(US10214515, Example 7 | Methyl 5-(5-amino-4-(1H-in...)
Affinity DataIC50: 1.00E+4nMAssay Description:The following assay was used to determine the inhibition rate of the preferred compounds of the present invention to the kinase activity of the recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent