BDBM35724 benzazepine derivative, 33

SMILES COc1cc(NC(=O)c2ccccc2C)ccc1C(=O)N1CCCC(O)c2cc(Cl)ccc12

InChI Key InChIKey=ZATPFKWGNKFRHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35724   

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

LigandPNGBDBM35724(benzazepine derivative, 33)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Otsuka Pharmaceutical

LigandPNGBDBM35724(benzazepine derivative, 33)
Affinity DataIC50: 39nMAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2009
Entry Details Article
PubMed