BDBM35712 benzazepine derivative, 15

SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2cc(Cl)ccc12

InChI Key InChIKey=SLOLBGFWHJBZQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35712   

TargetVasopressin V2 receptor(Human)
Otsuka Pharmaceutical

LigandPNGBDBM35712(benzazepine derivative, 15)
Affinity DataIC50: 63nMpH: 7.4 T: 2°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Otsuka Pharmaceutical

LigandPNGBDBM35712(benzazepine derivative, 15)
Affinity DataIC50: 1.20E+3nMpH: 7.4 T: 2°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2009
Entry Details Article
PubMed