BDBM357009 5-Amino-N-(5-chloropyridin-2-yl)-1-(2-(2-methoxypyridin-4-yl)phenyl)-1H-pyrazole-4-carboxamide::US10214509, Example 197

SMILES COc1cc(ccn1)-c1ccccc1-n1ncc(C(=O)Nc2ccc(Cl)cn2)c1N

InChI Key InChIKey=YOSGDVIVCBOVNI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357009   

TargetSodium channel protein type 9 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM357009(5-Amino-N-(5-chloropyridin-2-yl)-1-(2-(2-methoxypy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM357009(5-Amino-N-(5-chloropyridin-2-yl)-1-(2-(2-methoxypy...)
Affinity DataIC50: 3.30E+4nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent