BDBM357008 5-Amino-N-(5-chloropyridin-2-yl)-1-(2-(pyridin-3-yl)phenyl)-1H-pyrazole-4-carboxamide::US10214509, Example 196

SMILES Nc1c(cnn1-c1ccccc1-c1cccnc1)C(=O)Nc1ccc(Cl)cn1

InChI Key InChIKey=DXKCJRMOFZFQDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357008   

TargetSodium channel protein type 9 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM357008(5-Amino-N-(5-chloropyridin-2-yl)-1-(2-(pyridin-3-y...)
Affinity DataIC50: 700nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM357008(5-Amino-N-(5-chloropyridin-2-yl)-1-(2-(pyridin-3-y...)
Affinity DataIC50: 1.70E+4nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent