BDBM357004 5-Amino-N-(5-chloro-2-pyridyl)-1-(3-fluoro-2-methylphenyl)-3-methyl-pyrazole-4-carboxamide::US10214509, Example 137

SMILES Cc1nn(c(N)c1C(=O)Nc1ccc(Cl)cn1)-c1cccc(F)c1C

InChI Key InChIKey=RZGDNQIOOQDAAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 357004   

TargetSodium channel protein type 9 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM357004(5-Amino-N-(5-chloro-2-pyridyl)-1-(3-fluoro-2-methy...)
Affinity DataIC50: 600nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM357004(5-Amino-N-(5-chloro-2-pyridyl)-1-(3-fluoro-2-methy...)
Affinity DataIC50: 3.30E+4nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
US Patent