BDBM3570 8-[(3-Bromophenyl)amino]-1H-imidazo[4,5-g]quinazoline::Anilinopyrimidine deriv. 7a::CHEMBL66031::Imidazoquinazoline deriv. 8::N-(3-bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-amine

SMILES Brc1cccc(Nc2ncnc3cc4nc[nH]c4cc23)c1

InChI Key InChIKey=BZHDPIVTQKXAQQ-UHFFFAOYSA-N

Data  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 3570   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3570(N-(3-bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-am...)
Affinity DataIC50: 0.00800nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3570(N-(3-bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-am...)
Affinity DataIC50: 0.00800nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Protana

Curated by ChEMBL
LigandPNGBDBM3570(N-(3-bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-am...)
Affinity DataKd:  1.52E+4nMAssay Description:Equilibrium binding constant for EPH receptor B2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Protana

Curated by ChEMBL
LigandPNGBDBM3570(N-(3-bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-am...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of EPH receptor B2 using ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Spanish National Cancer Research Centre (Cnio)

Curated by ChEMBL
LigandPNGBDBM3570(N-(3-bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-am...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of MNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM3570(N-(3-bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-am...)
Affinity DataIC50: 4.00E+3nMAssay Description:Concentration required to inhibit the human liver recombinant fructose-1,6-bisphosphatase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed