BDBM356998 5-Amino-1-(3-fluoro-2-methylphenyl)-N-(5-(trifluoromethoxy)pyridin-2-yl)-1H-pyrazole-4-carboxamide::US10214509, Example 55

SMILES Cc1c(F)cccc1-n1ncc(C(=O)Nc2ccc(OC(F)(F)F)cn2)c1N

InChI Key InChIKey=XDPLDVHDEHHRMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356998   

TargetSodium channel protein type 9 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM356998(5-Amino-1-(3-fluoro-2-methylphenyl)-N-(5-(trifluor...)
Affinity DataIC50: 500nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM356998(5-Amino-1-(3-fluoro-2-methylphenyl)-N-(5-(trifluor...)
Affinity DataIC50: 3.30E+4nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent