BDBM356996 5-Amino-N-(4-chloro-2-fluoro-phenyl)-1-(o-tolyl)-1H-pyrazole-4-carboxamide::US10214509, Example 7

SMILES Cc1ccccc1-n1ncc(C(=O)Nc2ccc(Cl)cc2F)c1N

InChI Key InChIKey=NOIVKFYZKCOCBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356996   

TargetSodium channel protein type 9 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM356996(5-Amino-N-(4-chloro-2-fluoro-phenyl)-1-(o-tolyl)-1...)
Affinity DataIC50: 300nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Almirall

US Patent
LigandPNGBDBM356996(5-Amino-N-(4-chloro-2-fluoro-phenyl)-1-(o-tolyl)-1...)
Affinity DataIC50: 3.30E+4nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent