BDBM35698 5H-1-benzazepin-5-ylidene acetamide, 10e

SMILES FC1(F)CCN(C(=O)c2ccc(cc2Cl)-n2ccc(n2)-c2ccccc2)c2ccccc2\C1=C\C(=O)NCc1ccccn1

InChI Key InChIKey=FTHTYNFLAITHRR-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35698   

TargetVasopressin V2 receptor(Human)
Astellas Pharma

LigandPNGBDBM35698(5H-1-benzazepin-5-ylidene acetamide, 10e)
Affinity DataKi:  11nM ΔG°:  -10.8kcal/mole EC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2009
Entry Details Article
PubMed