BDBM35691 5H-1-benzazepin-5-ylidene acetamide, 1s

SMILES CCCNC(=O)\C=C1\c2ccccc2N(CCC1(F)F)C(=O)c1ccc(cc1Cl)-n1ccc(C)n1

InChI Key InChIKey=VTHPUFGBIATHEY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35691   

TargetVasopressin V1a receptor(Human)
Astellas Pharma

LigandPNGBDBM35691(5H-1-benzazepin-5-ylidene acetamide, 1s)
Affinity DataKi:  13nM ΔG°:  -10.8kcal/moleT: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Astellas Pharma

LigandPNGBDBM35691(5H-1-benzazepin-5-ylidene acetamide, 1s)
Affinity DataKi:  18nM ΔG°:  -10.5kcal/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2009
Entry Details Article
PubMed