BDBM35681 5H-1-benzazepin-5-ylidene acetamide, 1i

SMILES Cc1ccn(n1)-c1ccc(C(=O)N2CCC(F)(F)\C(=C/C(=O)NCc3cccc(n3)C#N)c3ccccc23)c(Cl)c1

InChI Key InChIKey=IKROSHQRMVKMPT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35681   

TargetVasopressin V2 receptor(Human)
Astellas Pharma

LigandPNGBDBM35681(5H-1-benzazepin-5-ylidene acetamide, 1i)
Affinity DataKi:  7.40nM ΔG°:  -11.0kcal/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Astellas Pharma

LigandPNGBDBM35681(5H-1-benzazepin-5-ylidene acetamide, 1i)
Affinity DataKi:  22nM ΔG°:  -10.4kcal/moleT: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2009
Entry Details Article
PubMed