BDBM35680 5H-1-benzazepin-5-ylidene acetamide, 1h

SMILES CN(C)c1cccc(CNC(=O)\C=C2\c3ccccc3N(CCC2(F)F)C(=O)c2ccc(cc2Cl)-n2ccc(C)n2)n1

InChI Key InChIKey=OHQLZPXJQBKSLE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35680   

TargetVasopressin V2 receptor(Human)
Astellas Pharma

LigandPNGBDBM35680(5H-1-benzazepin-5-ylidene acetamide, 1h)
Affinity DataKi:  11nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Astellas Pharma

LigandPNGBDBM35680(5H-1-benzazepin-5-ylidene acetamide, 1h)
Affinity DataKi:  48nM ΔG°:  -9.98kcal/moleT: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2009
Entry Details Article
PubMed