BDBM356536 N-Pyridin-3-yl-4-(4-{1-[3-({([(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]-1H-benzimidazol-5-yl}-1H-pyrazol-1-yl)piperidine-1-carboxamide::US10213427, Example 25::US10813930, Ex. No. 25

SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-n1cnc2cc(ccc12)-c1cnn(c1)C1CCN(CC1)C(=O)Nc1cccnc1

InChI Key InChIKey=DSJFWAIUKZCFGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356536   

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM356536(N-Pyridin-3-yl-4-(4-{1-[3-({([(2,2,2-trifluoroethy...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM356536(N-Pyridin-3-yl-4-(4-{1-[3-({([(2,2,2-trifluoroethy...)
Affinity DataIC50: 10nMAssay Description:FGFR3 Enzymatic Assay The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
Go to US Patent