BDBM356530 N-[3-(5-{4-[2-(3-Cyanopyrrolidin-1-yl)-1-methyl-2-oxoethyl]phenyl}-1H-benzimidazol-1-yl)phenyl]-N′-(2,2,2-trifluoroethyl)urea::US10213427, Example 19::US10813930, Ex. No. 19

SMILES CC(C(=O)N1CCC(C1)C#N)c1ccc(cc1)-c1ccc2n(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1

InChI Key InChIKey=AMFAWFZBNVXZSN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356530   

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM356530(N-[3-(5-{4-[2-(3-Cyanopyrrolidin-1-yl)-1-methyl-2-...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM356530(N-[3-(5-{4-[2-(3-Cyanopyrrolidin-1-yl)-1-methyl-2-...)
Affinity DataIC50: 10nMAssay Description:FGFR3 Enzymatic Assay The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2021
Entry Details
Go to US Patent