BDBM356501 6-(4-fluorophenyl)-2-oxo-N-(5- phenylpentyl)-1,3- benzoxazole-3-carboxamide::US10213416, Example 1

SMILES Fc1ccc(cc1)-c1ccc2n(C(=O)NCCCCCc3ccccc3)c(=O)oc2c1

InChI Key InChIKey=PARRCXQSHYYGNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356501   

TargetAcid ceramidase(Human)
University of Chicago

US Patent
LigandPNGBDBM356501(6-(4-fluorophenyl)-2-oxo-N-(5- phenylpentyl)-1,3- ...)
Affinity DataIC50: 75nMAssay Description:hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% No...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent