BDBM355947 (S)-1-(5-chloro-6- (2H-1,2,3-triazol-2- yl)pyridin-3-yl)-3-(7- (1-methoxyethyl)-2- methylpyrazolo[1,5- a]pyrimidin-6-yl)urea::US10442808, Example 71::US9815842, Example 71

SMILES CO[C@@H](C)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(C)nn12

InChI Key InChIKey=JMBZOZYUNAOJAG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355947   

LigandPNGBDBM355947(US9815842, Example 71 | (S)-1-(5-chloro-6- (2H-1,2...)
Affinity DataIC50: 0.00500nMAssay Description:IC50 values of test compounds were determined with an enzyme activity assay using the C-domain of MALT1 (amino acids 329-824). The readout parameter ...More data for this Ligand-Target Pair
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Date in BDB:
10/14/2019
Entry Details
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LigandPNGBDBM355947(US9815842, Example 71 | (S)-1-(5-chloro-6- (2H-1,2...)
Affinity DataIC50: 0.00500nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent