BDBM355876 N-(4-((5-(3-cyanomethylphenyl)pyrrolo[1,2-b]pyridazin-4-yl)oxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide::US9815840, Example 85

SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnn4ccc(-c5cccc(CC#N)c5)c34)c(F)c2)cc1

InChI Key InChIKey=SALVLCSMLVJVQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355876   

TargetHepatocyte growth factor receptor(Human)
The Asan Foundation

US Patent
LigandPNGBDBM355876(US9815840, Example 85 | N-(4-((5-(3-cyanomethylphe...)
Affinity DataIC50: 40nMAssay Description:The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...More data for this Ligand-Target Pair
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Date in BDB:
10/14/2019
Entry Details
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