BDBM355858 N-(3-fluoro-4-((5-(3-(1-hydroxyethyl)phenyl)pyrrolo[1,2-b]pyridazin-4-yl)oxy)phenyl)-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridin-3-carboxamide::US9815840, Example 47

SMILES CC(O)c1cccc(c1)-c1ccn2nccc(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)c12

InChI Key InChIKey=CLLKMCVXNICMQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355858   

TargetHepatocyte growth factor receptor(Human)
The Asan Foundation

US Patent
LigandPNGBDBM355858(US9815840, Example 47 | N-(3-fluoro-4-((5-(3-(1-hy...)
Affinity DataIC50: 40nMAssay Description:The inhibitory effect of the compounds of the present invention on the activity of c-Met was confirmed as follows.Specifically, 250 μM G4Y1 pept...More data for this Ligand-Target Pair
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Date in BDB:
10/14/2019
Entry Details
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