BDBM355732 Azetidin-1-yl[3-(4-chloro-3,5-difluorophenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methanone::US9815832, 9

SMILES Fc1cc(cc(F)c1Cl)-n1c(nc2cccnc12)C(=O)N1CCC1

InChI Key InChIKey=RJRKJHOEVRBWEF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355732   

LigandPNGBDBM355732(US9815832, 9 | Azetidin-1-yl[3-(4-chloro-3,5-diflu...)
Affinity DataIC50: 14.2nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent

LigandPNGBDBM355732(US9815832, 9 | Azetidin-1-yl[3-(4-chloro-3,5-diflu...)
Affinity DataIC50: 420nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2019
Entry Details
US Patent